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Zaven Khachaturian, PhD, Editor-in-Chief
451 Hungerford Drive, Suite 119-355
Rockville, MD 20850
Tel: 301-294-7201
Fax: 301-294-7203
E-mail: ADJ@kra.net
Ara Khachaturian, PhD, Executive Editor
Tel: 301-309-6730
Fax: 301-294-7203
E-mail: ADJ_MgrEd@kra.net
Information for Authors
Aims & Scope:
The mission of Alzheimer's & Dementia: The Journal of the
Alzheimer's Association (Alzheimer's & Dementia) is to bridge
the knowledge gaps across a
wide range of bench-to-bedside
investigation. Alzheimer's & Dementia publishes the results of
studies in: behavior, biochemistry,
genetics, molecular biology,
pharmacology, physiology, protein chemistry, neurology, neuropathology,
psychiatry, geriatrics, neuropsychology,
epidemiology,
sociology, health services research, health economics, political
science and public policy. Alzheimer's & Dementia
emphasizes
interdisciplinary investigations and integrative/translational articles
related to: etiology, risk factors, early detection,
disease modifying
interventions, prevention of dementia, and applications of
new technologies in health services. The Journal
will publish only
original contributions in the following forms: • comprehensive
reviews; • research articles; • information
on clinical trials; •
short reports; • in-depth perspectives/open-peer commentaries; •
theoretical and/or translational
papers that attempt to integrate
knowledge across disciplines; • history and politics of science/
brief biographies, and •
abstracts of papers presented at international
meetings.
Negative results, particularly clinical trials, are
published as short
communications.
The ultimate objective is to create a novel forum for: • rapid
communication of new findings, ideas or perspectives; • disseminating
knowledge, across the spectrum of basic to clinical studies,
necessary for optimal translation of research findings
into practical
applications/interventions; • integrating knowledge across disciplines;• increasing knowledge in diverse disciplines
to promote
early detection/diagnosis and/or interventions; • formulating new
theories and/or strategies for the rigorous testing
of theories or
their predictions; • identifying promising new directions of research;
and • providing the scientific impetus
for new initiatives or
public policies concerning research on prevention and new models
of health services.
Instructions for
Authors
Review Articles:
Comprehensive Reviews are commissioned papers by the editors to provide comprehensive
and balanced coverage of a timely and/or controversial issue by a recognized authority. The invited review should integrating different
points of view on ground-breaking, fast-moving or contentious topics with the objective of translating, informing or educating a wide
multi-disciplinary audience about varying perspective. Reviews should provide a brief overview or background of critical issues
and then concentrate on setting recent findings in context. It is crucial for all Reviews, particularly those tackling controversial
topics, to provide a well-balanced view of developments; authors must never concentrate unduly on their own research. Reviews,
unlike Research Articles, do allow some speculation designed to foster the formulation or testing of new hypothesis.
Reviews
must include an abstract of approximately 150 words. Length may not exceed 15,000 words, a maximum of 60 references, no more than six
figures, boxes or tables.
Perspectives and Open-Peer Commentaries:
Perspectives and open-peer commentaries
provide personal in-depth viewpoints, rather than a review, on hotly debated topics; controversial theoretical, research or policy issues.
Perspectives should: a) stimulate debate, b) present new models or hypotheses, c) suggest future experiments, directions of
research or policies and/or, d) speculate on the meaning/interpretation of new discoveries/data. Articles that merely outline recent
advances rather than provide a though provoking opinion on them are not suitable for this section of the journal.
Perspectives must include an abstract of approximately 150 words. Length of a Perspective article may not exceed 5,000 words, a maximum
of 50 references, no more than six figures, boxes or tables. Open-peer commentaries may include an abstract of approximately
150 words. Length of Open-Peer Commentaries may not exceed 1,500 words, a maximum of 20 references, no more than two
figures, boxes or tables.
Research Articles:
Research articles cover hypothesis driven research or evidence-based
validation studies in any of the following generic areas of study: Biology, Chemistry, Clinical/Medical Interventions, Behavior/Neuropsychology,
Social Sciences, Nursing, Health Economics, Health Services Research and Public Policy. Manuscripts should include: a) Structured Abstract,
b) Background, c) Methods, d) Results, e) Discussion, f) References, g) Acknowledgements/Conflicts/Funding Sources and, h) Key Words.
The manuscript, and specifically the abstract, should be written such that a diverse audience will understand the central research question
and the significance of the findings or conclusion of the study.
Research articles must include an abstract of approximately
150 words. Length may not exceed 10,000 words, a maximum of 50 references, no more than six figures, boxes or tables.
Short
Reports:
Short Reports are brief communications dealing with Case Studies or information on Clinical Trials [including
the negative results and/or adverse events in clinical studies]. Short Reports will also cover brief articles on the utility
or potential applications of a new technique, instruments or analytical approaches; rather than the detail of the technique per se, which
can be references for readers interested in complete technical details. These articles should educate and inform readers by comparing
or contrasting new approaches/techniques with established ones and highlighting the pros and cons of each.
Short Reports
must include an abstract of approximately 150 words. Length may not exceed 1,500 words, a maximum of 20 references, no more than two
figures, boxes or tables.
Policy Forum:
Policy Forum manuscripts generally will cover topic related to "Science
and Society" that might be relevant and/or interest to a broader audience. Policy Forum will include papers on: history
and politics of science, brief biographies and policy analysis. The main aim of the Policy Forum articles is simply to tell
an exciting story on an interesting topic; the style should be conversational and newsy.
Length may not exceed 5,000 words, a maximum
of 50 references, no more than six figures, boxes or tables.
Letters:
Letters are welcomed brief communications
relating to the content of earlier issues of ADJ or general topics of interest. Letters relating to earlier issues of ADJ will
be sent to the appropriate authors for review and to give them an opportunity to reply. Previously unpublished data, however, will not
be considered.
Length may not exceed 750 words, a maximum of 10 references, no more than one figure.
Research News:
Research News is designed to highlight recent events, advances or developments (e.g., grants awarded, new funding opportunities,
calendar of events, conference reports and abstracts of papers presented at international meetings) that might be a particular interest
to the research community. The articles should inform not only a general audience but also offer an expert a balanced interpretation
of the advances, developments or events being reported. The article should be restricted to report only novel and interesting information.
Articles should be written in a lively style, giving brief essential background, putting recent advances in context and providing insight
on future perspectives and direction. Rather than including extensive background information, the reader should be directed, via a citation,
to an appropriate review article or text.
Research News articles must include a "summary lead" that may not exceed 50 words.
The summary lead is the first few sentences that summarizes the event and answers the questions: Who? What? When? Where? Why? How?
Length may not exceed 1,500 words, a maximum of 20 references, no more than two figures, boxes or tables.
Manuscript
Submission
: Alzheimers & Dementia uses a Web-based
online manuscript submission and review system. Please
visit
 http://ees.elsevier.com/adj/ to submit your manuscript electronically.
The Web site guides authors stepwise through the
creation
and uploading of the various files. Note that original source
files, not PDF files, are required. Authors may send queries concerning
the submission process manuscript status or journal procedures
to the Editorial Office. Once the submission files are
uploaded the system
automatically generates electronic (PDF)
proof, which is then used for reviewing. All correspondence,
including the Editor's decision
and request for revisions, will be by
e-mail. Articles will be published in English. International authors
who are not fluent in the
English language should seek help in the
preparation of their manuscripts. Such assistance will enhance the
review process and greatly
reduce the time to publication, if the
article is accepted.
Provisional or final acceptance is based on originality, scientific
accuracy,
relevance, clarity, and topical balance of the Journal.
Authors should suggest the names (with contact information) of
5-7 potential
reviewers for the manuscript. Every attempt will be
made to use at least one suggested reviewer. A request to submit
a revised manuscript
does not guarantee acceptance of the revised
manuscript, only that it will be reconsidered by the reviewers.
Decisions will be communicated
to the corresponding author by
email.
The Elsevier Author Gateway [ http://authors.elsevier.com ] provides
a
means to track accepted articles and set up e-mail alerts to
inform you of when an article's status has changed. You can find
detailed
artwork guidelines, copyright information, frequently
asked questions and more. Contact details for questions arising
after acceptance
of an article, especially those relating to proofs,
are provided after registration of an article for publication.
Responsibilities
of Authorship
: As a condition of authorship, all
authors must be willing to take responsibility for the entire manuscript.
Multi-authored
manuscripts should have a declaration of
each author's contributions in the submission cover letter. The
form will be sent to the corresponding
author when the manuscript
is received by the Publisher.
Copyright
: Publications are copyrighted for the protection
of the
authors and the publisher. A Transfer of Copyright Agreement will
be sent to the author who submits the manuscript. The corresponding
author must sign and returned the completed form transferring
copyright ownership of the manuscript to Elsevier Inc. before the
article
can be published.
Conflict of Interest Disclosure
: The authors should disclose any
relationships that might have the
appearance of a "conflict of
interest" on the title page of the paper. Should there be any
financial association [e.g., grants, contracts,
consultancy, honoraria,
advisory board memberships, equity share, etc] between any
of the authors and the financial beneficiaries [e.g.,
commercial
company] of a product that figures prominently or is discussed in
the article, the author(s) should disclose such association.
Editors
reserve the right to reject an article on the basis of a significant
conflict of interest. If the article is accepted for publication,
the
disclosure statement may be published. When no competing interests
are present the disclosure statement should confirm such.
Ethics—Protection
of Human Subjects and Animal Welfare
: Authors
should comply with all the relevant provisions of the National
Institutes of Health
(NIH) Grants Policy Statement concerning:
Ethical and Safe Conduct in Science and Organizational
Operations, Requirements Affecting the
Rights and Welfare of
Individuals as Research Subjects, Patients or Recipients of Service,
and Animal Welfare guidelines outlined in
the "Public Policy
Requirements and Objectives" [ see http://grants.nih.gov/grants/policy/nihgps_2003/index.htm ]
Permissions
:
The inclusion of any copyrighted material or previously
published material [e.g., direct quotations, tables, or illustrations]
must be
accompanied by written permission for use from
the copyright owner and original authors along with complete
information about the original
source. Authors are responsible for
obtaining permission and payment of any fees associated with
reuse.
Potential Reviewers
:
Authors are encouraged to suggest the names
of potential peer-reviewers that do not have any conflicts to assist
with a prompt and fair
review process. The submission letter
should include the names, mailing addresses, phone and fax numbers,
and e-mail addresses of 5-7
potential reviewers with appropriate
expertise to evaluate the manuscript.
Proofs
: Corrections to the proofs greater
than 10% will be charged
to the author. Authors will not be held accountable for errors that
occur in the production or print processes.
Offprints
: Offprint order forms will be sent to authors before
articles are published. Reprints in quantity must be purchased
from
the publisher.
Embargo — Public Presentation/Media Releases
: All manuscripts
accepted for publication in Alzheimer's & Dementia will be embargoed
until the posted publication date/time by Elsevier. Authors
and their institutions
are expected to abide by the copyright agreement
and refrain from disclosing to media or the public findings of
an accepted manuscript
prior to embargo period [publication].
Style of Manuscript
General Format
:
- Manuscripts
should be typed double-spaced, and numbered,
with wide margins. Computer-generated illustrations must be
of the high quality of professional
line drawings or they will
not be accepted.
- The title page should contain: title of paper; author(s); laboratory
or institution
of origin with city, state, zip code, and
country; complete address for mailing proofs; telephone, fax
number, and email address (when
available, the email address
will appear in the correspondence footnote of the published
article).
- References, footnotes, and
legends for illustrations should be
typed on separate sheets, double spaced.
- Illustrations should be identified with figure
number and author(
s) name; when necessary the top should be clearly
marked.
- Each table should be typed on a separate sheet
and double
spaced.
- All dimensions and measurements must be specified in the
metric system. Standard nomenclature, abbreviations
and
symbols, as specified by Royal Society Conference of Editors.
Metrication in Scientific Journals. Am. Scient. 56:159-
164; 1968,
should be used throughout.
- Italics should not be used for the purpose of emphasis.
- Brief Communications should be
restricted to six typewritten
pages, including references, and should not present more than
one figure and one table, or two figures,
or two tables.
Title
: The title should not be longer than 85 characters, including
spaces between words.
Only the first word of the title should be
capitalized.
Length of Paper
: The Editors insist upon clear, concise statement
of facts and conclusions. Fragmentation of material into numerous
short reports is discouraged. All accepted papers are subject to
editorial
revision and copyediting. Authors should avoid redundancy
between sections of text and illustrations and text. The
Editors may recommend
that appendices and tables containing
extensive data be published in the electronic version of Alzheimer's & Dementia and
only referenced in a footnote in the print
edition.
Abstract
: Each paper submitted must be accompanied by a structured
abstract of 250 words or less to appear after the title. The
abstract should be suitable for use by abstracting journals and must
include
the following headings: Background, Methods, Results,
and Conclusion(s). A list of 5-15 keywords or short phrases suitable
for indexing
terms should be typed at the bottom of the
abstract page accompanying the manuscript. These terms will be
printed with the paper following
the abstract.
Headings
: All headings should be numbered, for example, 1.
Introduction, 2. Methods, 2.1. Study population,
etc. Capitalize the
first word only for all headings.
Footnotes
: If more than one author, the corresponding author
should be indicated with an asterisk. If there is more than one
affiliation, use a superior letter for each one. Use superior numbers
for any other footnotes to authors' names, such as a current
address. Text footnotes should not be used; the material should be
incorporated
into the text. Table footnotes: see Tables.
Abbreviations
: Complex terms used frequently in the manuscript
may be
abbreviated. The manuscript should include a list of all
abbreviations used. Abbreviations are placed in parentheses at first
use in
the abstract and again at first use in the text.
References
: References should not exceed 50 in number. Reference
format should conform to that set forth in "Uniform Requirements
for Manuscripts Submitted to Biomedical Journals" ( http:// www.icmje.org
) and journal abbreviations should conform to the
style used in the Cumulated Index Medicus. Cite references, figures,
and tables
in numeric order according to the first mention in
the text. Accuracy of reference data is the responsibility of the
author. Verify all
references against
original
sources. "In press"
citations must have been accepted for publication and the name
of
the journal or book publisher must be included. The style of
citation should be as follows:
Journals: authors' last names
and initials; title of article;
journal name; date; volume number, and inclusive pages (list
all authors when six or fewer; when seven
or more, list six
and add et al):
Graeber GM, Gupta NC, Murray GF. Positron emission tomographic
imaging with fluorodeoxyglucose is
efficacious in
evaluating malignant pulmonary disease. J Thorac Cardiovasc
Surg 1999;117:719-27.
Lytle BW, Blackstone EH, Loop FD,
Houghtaling PL, Arnold
JH, Akhrass R, et al. Two internal thoracic artery grafts are
better than one. J Thorac Cardiovasc Surg 1999;117:855-72.
Books: authors' last names and initials; chapter title, editor's
name, book title, edition, city, publisher, date, and pages:
Mollnes TE. Analysis of in vivo complement activation: In:
Herzenberg LA, Weir DM, Herzenberg LA, Blackwell C,
editors. Weir's Handbook
of experimental immunology. Volume
78, 5th ed. Boston: Blackwell Science; 1997, p. 78.1-
78.8.
Acknowledgments
: Authors
must provide proper recognition to
public funding agencies [e.g., agency name, grant title and number]
and/or private funding source
or the sponsor of the study as
well as those that made significant contribution to the project.
Figures
: Figures must
be of professional quality. When possible,
please use or supply first-generation artwork. Figures are encouraged
in electronic format
with a printed proof on glossy or highquality
photographic printer paper and should be at least 5 inches
wide. Figures may be black and
white line art, graphs, halftones
(photographs), or color. TIFF, EPS, or PDF formats are recommended
for electronic artwork. Line art
should have a minimum
resolution of 1000 dpi, halftone art a minimum of 300 dpi, and
combination art (line/halftone) a minimum of 500
dpi. MS Office
files (Word, PowerPoint, and Excel) are also accepted if they meet
certain standards. Color figures should be submitted
in actual size
and authors will be responsible for costs associated with color
reproduction.
When possible all lettering should be
within the frame-work of the
illustration; likewise the key to symbols should be on the face of
the chart. The following standard symbols
should be used as they
are easily available to the printer: + ? ? [] ?. Actual magnification
of all photomicrographs
should be provided. Dimension scale
should be indicated.
For help with preparing electronic artwork for both on-screen
review and
eventual publication visit the Elsevier Author Gateway
[ http://authors.elsevier.com ].
Video Clips Alzheimer's & Dementia encourages authors to submit video clips to be published on the Journal's website at www.alzheimersanddementia.org as illustrations incorporated into articles for publication in the print journal. All video clips are subject to peer review.
The following file formats are accepted:
• MPEG-1 or MPEG-2 (.mpg)
• QuickTime (.mov)
• Audio/Video
Interface (.avi)
• CompuServe GIF (.gif)
Alzheimer's & Dementia does not edit video clips, but reviewers may
suggest changes.
Requirements:
• Maximum cumulative length of videos or animated computer graphics is 4.5 minutes.
• Files may be divided into several smaller clips not to exceed 4.5 minutes in total.
• Each video segment file
cannot exceed 50 MB. The submission program will time out if the file size is larger than 50 MB.
• Please ZIP the file and
upload the zipped file to hasten the upload time.
• If the video or animation is divided into several clips:
• Identify
each clip at the beginning of the section, e.g., Video Clip 1.
• Each clip or graphic should be saved as a separate file.
• Complete legends for each video clip must be included in the manuscript.
• Videos must be cited in the text of
the manuscript.
• Sound tracks may be included as appropriate.
Tables
: Table numbers should be Arabic,
followed by a period and
a brief heading. Explanatory matter should be in footnotes, not as
part of the title. Begin each table on a
separate page. Use same size
type as in text where possible. Supply a brief heading for each
column. Do not use vertical lines between
columns. Use horizontal
lines above and below the column headings and at the bottom of
the table only. Use extra space to delineate sections
within the
table. Abbreviations used in the table must be defined in a footnote
to the table. Indicate footnotes in this order: *,
†, ‡, §, ¶, #, **, ††,‡‡, §§, ¶¶, ##. Table footnotes
should be indicated in the body of
the table in order of their appearance with superior letters. Statistical
measures should be indicated
with symbols: *, **, etc. Tables
must not duplicate material in text or illustrations. Statistical measures
of variation, SD, SE, etc.,
should be identified. Analysis of
variance tables should not be submitted but significant F's should
be incorporated where appropriate
within the text. The appropriate
form for reporting F value is: F (11, 20) = 3.05, p < 0.01.
Formulas and Equations
:
Structural chemical formulas, process
flow-diagrams, and complicated mathematical expressions should
be kept to a minimum. Usually chemical
formulas and flowdiagrams
should be provided for reproduction as line cuts. All
subscripts, superscripts, Greek letters, and unusual
characters must
be clearly identified.
Drugs
: When possible, provide generic rather than trademarked
names of drugs.
Proprietary (trademarked) names should be capitalized.
The chemical name should precede the trade, popular
name, or abbreviation of a
drug the first time it occurs. Trade
names of drugs and other products must not appear in the title. The
trade name may appear once in
the abstract and once in the
introduction or methods section; all other mention of the product
must be in the form of the generic name.
Anesthesia
: In describing surgical procedures on animals, the type
and dosage of the anesthetic agent should be specified.
Curarizing
agents are not anesthetics; if these were used, evidence must be
provided that anesthesia of suitable grade and duration was
employed.
Updated January 2010
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